Hunting vigorously through the lazylaces archives for "point'n'click" unearthed the following results...
The Other Side Of The Door is both the title, and goal, of this escape the room style point'n'click game. It looks simple but the fact that's the text is Japanese (?) should make things a little trickier though [subbed by winniethepooh].
point'n'click game addict you probably think you know everything there is to know about Trapped Part 1: The White Rabbit when I say that the game starts with you waking up in a strange (and don't forget locked) room. You probably wouldn't even be fazed by the dead body next to you. But there's something a little bit more to this game. And I'm not just talking about the fact that there's more than one room. It has a quirky style all of it's own, that takes a little bit of getting used to, but ultimately it's very endearing. And don't be put off by the isometric graphics, it might look like it uses some annoying key combo to navigate around that'll have you continually crashing into walls and falling into traps when you didn't mean to, but that's not the deal here at all - all the navigation is proper point'n'click and as a nice touch you find/pick up objects just by walking into them. You'll soon have a full inventory without even a sniff of pixel hunting. Enjoy - and then, like me, eagerly await the promised next two episodes [subbed by Oo, SH, angela, Nicole, troy & winniethepooh].
Dungeon Banner Escape is a little mini escape the room style (when I say room, I really mean dungeon, obviously) point'n'click game from the same folks that brought you the SSSG Series, and it's in a banner format a la Jayis [subbed by roko & kaylou].
escape the room one too many times I'm now seeing double in Collaboration Escape [subbed by Nicole & winniethepooh].
Wogger Mini 84 [subbed by hiddenfaceinthecrowd, Chili, Sentinel, Cruzinn, Teakay, BigBadDave & Mantari].
Escape Logic involves you solving logic puzzles to escape the room. Of course what would be more logical would be to stop getting trapped in these rooms all the time. But that would be no fun [subbed by f00].
point'n'click cooking to do in Esklavos C7. Pass me the balsamic vinegar... [subbed by Mantari, vmklover, She-Nomad & higgo]. NOTE: When I tried playing this it took a few attempts to get it to load due to the large number of people trying to play. Persist if you don't get it to load first time, it's worth it.
point'n'click it would be awesome (also it would be very time consuming trying to leave any room that you were in). Anyway while the boffins work on that one we can play SSSG: Sneaky Land 4: Incidia instead [subbed by Self Defiant, She-Nomad, Robi, Jumisa, Big Bad Dave & anon].
Magenta Green Room (there seem's to be some confusion over the name, but unless I've gone colour blind it's green) is an escape the room style point'n'click game. The room is Green. You must escape it. You do that by pointing. And clicking. You know sometimes these game descriptions pretty much just write themselves...*takes well deserved break* [subbed by Werewolf].
UPDATE: OK, I don't know what was going on at newgrounds. The game I linked was the green room, the page title said magenta, confusing enough, but then they swapped it back to the magenta room game to match the title. Anyways, I've updated the link now so it goes to the right place.
Gymnasium Escape is a Japanese point'n'click game that looks great, but unfortunately has quite a large language barrier that makes playing it a little tricky. All I've managed to work out so far is how to turn on the power in the storeroom, and I was quite impressed with that. Perhaps between us we can work out what is going on here... [subbed by f00].
Shut.In" (featuring new escape the room games every day) has started it's own series of exclusive point'n'click games called "Locked In" (in which, unsurprisingly, you have to... wait for it... wait for it... escape the room... ahhhh...). I'm assuming this first episode was built by the same people who did the puzzled series as it's very similar to, but not entirely the same as, Puzzled 4 [subbed by Mystery].