Hunting vigorously through the lazylaces archives for "point'n'click" unearthed the following results...
Loondon is a slightly more loony version of London, or maybe slightly less loony depending on how you look at it (nobody voted Boris for Mayor in Loondon), with beautiful, but somewhat sad, graphics and soundtrack [subbed by myuhinny].
Homework Escape... because homework is a great thing to escape from [subbed by buji].
Chazkenger & Henteko House is slightly weird, in the same way that the economy is slightly depressed [subbed by Cyberjar88].
Plastic Beach, there's allegedly an adventure to be had, or just poke around the random weirdness, and listen to the new album from Gorillaz. Guess which approach lazylaces took? [subbed by Sal Davies].
Leprechaun's Gold was one of the original, later rejected, names for Lucky Charms [subbed by buji].
Escher 1 - Chromatophobia [subbed by Sassy].
Antiquities Store House you can find the crate containing the ark and thus kick off a whole 'crystal skull' adventure... [subbed by zen].
LOLCat Escape iz irritating on many, many different levelz [subbed by maggie].
The Soulmates is an interactive point'n'click adventure story, with rudimentary graphics, poor voice acting, a bad soundtrack, and a dubious plot. At the same time though, and rather improbably, it manages to be bizarrely good. Watch out for a little 'language' though [subbed by anon].
Dad Escape a few times to get it to work, it's worth it though as otherwise you'll have to pluck ponderously at your own acoustic guitar [subbed by zen].
go West in Tangerius 2 I make sure that I never close my eyes as I don't know what kind of adventure will befall me [subbed by buji].
Find the Escape Men 7 you have to escape the lavatory, which is ironic as after listening to the soundtrack for any length of time that's exactly where you'll be rushing to get into... [subbed by buji].